Sugi Predict

Sugi Predict / Compounds / SCHEMBL134309

SCHEMBL134309

SCHEMBL134309

O=P(c1ccc(P(=O)(c2cccc3ccccc23)c2cccc3ccccc23)cc1)(c1ccc2ccccc2c1)c1cccc2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ CMA1 P23946 3/20 0.38
▸ ACP3 P15309 2/20 0.38
▸ CTSG P08311 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.35
▸ HSD17B10 Q99714 2/20 0.35
▸ CYP2A6 P11509 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ CYP1B1 Q16678 1/20 0.35
▸ GPR84 Q9NQS5 1/20 0.34
▸ TOP1 P11387 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ PTK2B Q14289 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ HPRT1 P00492 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339291 0.97 LMNA (0.41) LMNAKDM4EPOLBCMA1ACP3
SCHEMBL14339288 0.97 LMNA (0.41) LMNAKDM4EPOLBCMA1ACP3
SCHEMBL14339293 0.94 LMNA (0.39) LMNAKDM4EPOLBCMA1ACP3
SCHEMBL11962401 0.92 KDM4E (0.42) LMNAKDM4EPOLBCMA1ACP3
SCHEMBL14339289 0.89 KDM4E (0.47) LMNAKDM4EPOLBACP3ALDH1A1
SCHEMBL17452052 0.88 ALDH1A1 (0.37) LMNAKDM4EPOLBCMA1ACP3
SCHEMBL19857353 0.87 ESR1 (0.43) LMNAKDM4EPOLBCMA1ACP3
SCHEMBL14339298 0.87 ALDH1A1 (0.38) LMNAPOLBALDH1A1HSD17B10HIF1A
SCHEMBL5437709 0.86 LMNA (0.47) LMNAKDM4EPOLBACP3ALDH1A1
SCHEMBL17451894 0.84 TOP1 (0.41) LMNAKDM4EPOLBCMA1ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535640-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-12-27 — — US disclosed
US-11145828-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-10-12 — — US disclosed
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-10-05 — — US disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 — — US disclosed
EP-3658564-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2021-05-19 — — EP disclosed
US-20200207794-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-07-02 — — US disclosed
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-02-13 — — US disclosed
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-26 — — US disclosed
US-20190252628-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-15 — — US disclosed
WO-2019020538-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-01-31 — — WO disclosed
US-9236578-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-01-12 — — US disclosed
US-9236578-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-01-12 — — US disclosed
US-20130168663-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-07-04 — — US disclosed
US-20130168663-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-07-04 — — US disclosed
US-20120056169-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2012-03-08 — — US disclosed
US-20120056169-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) 2012-03-08 — — US disclosed
US-7776455-B2 Organic electronic devices MERCK PATENT GMBH (DE) 2010-08-17 — — US disclosed
US-7776455-B2 Organic electronic devices MERCK PATENT GMBH (DE) 2010-08-17 — — US disclosed
US-20070170419-A1 Organic electronic devices MERCK PATENT GMBH (DE) 2007-07-26 — — US disclosed
US-20070170419-A1 Organic electronic devices MERCK PATENT GMBH (DE) 2007-07-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145828-B2 Metal complexes AP1M1, AP2M1, AP3M1 LMNA 4095/4885KDM4E 3877/4885POLB 1085/4885
US-20190252628-A1 METAL COMPLEXES AP1M1, AP2M1, AP3M1 LMNA 4095/4885KDM4E 3877/4885POLB 1085/4885
US-20190292210-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES AP2M1, MCU, AP3M1 LMNA 3190/4885KDM4E 4613/4885POLB 419/4885
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC LMNA 4536/4885KDM4E 3894/4885POLB 1110/4885
US-20200207794-A1 METAL COMPLEXES IMMT, MCU, SOD1 LMNA 4756/4885KDM4E 4470/4885POLB 1166/4885
US-11535640-B2 Metal complexes IMMT, MCU, SOD1 LMNA 4756/4885KDM4E 4470/4885POLB 1166/4885
US-11136343-B2 Binuclear metal complexes for use as emitters in organic electroluminescent devices AP2M1, MCU, AP3M1 LMNA 3190/4885KDM4E 4613/4885POLB 419/4885
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES BICRA, NCLN, IMMT LMNA 3421/4885KDM4E 3160/4885POLB 1117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.