SCHEMBL19769428

SCHEMBL19769428

c1ccc2c(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccc(-c7ccc(-n8c9ccccc9c9ccccc98)cc7)cc6)c5c43)cccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.40
HDAC4 P56524 1/20 0.39
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
PDE6D O43924 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 4/20 0.35
HPGD P15428 2/20 0.35
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
GSR P00390 1/20 0.34
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21566357 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL23203902 0.95 L3MBTL1 (0.44) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL19769464 0.92 KDM4E (0.46) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL24356579 0.90 HSD17B1 (0.39) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL19652851 0.90 L3MBTL1 (0.44) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL19769481 0.89 KDM4E (0.42) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL19769609 0.89 KDM4E (0.39) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL19769476 0.89 L3MBTL1 (0.39) KDM4EATML3MBTL1TDP1HDAC4
SCHEMBL17228250 0.89 KDM4E (0.55) KDM4EATML3MBTL1TDP1CNR1
SCHEMBL19769479 0.88 KDM4E (0.41) KDM4EATML3MBTL1TDP1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019409-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 KDM4E 4452/4885ATM 4365/4885L3MBTL1 4794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.