SCHEMBL197704

SCHEMBL197704

Clc1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.53
LMNA P02545 2/20 0.53
CYP3A4 P08684 2/20 0.52
MAPK1 P28482 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
KCNN4 O15554 3/20 0.52
ALDH1A1 P00352 2/20 0.41
KCNA3 P22001 2/20 0.38
CYP2A6 P11509 4/20 0.38
CYP1A2 P05177 4/20 0.38
CYP19A1 P11511 3/20 0.37
HTR2A P28223 2/20 0.37
HTR2C P28335 2/20 0.37
OPRK1 P41145 2/20 0.37
KCNH2 Q12809 2/20 0.37
ADRA1A P35348 1/20 0.37
MEN1 O00255 1/20 0.37
SLC22A1 O15245 1/20 0.37
NR1I2 O75469 1/20 0.37
GMNN O75496 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29617470 1.00 TSHR (0.53) TSHRLMNACYP3A4MAPK1TDP1
Fluoride SCHEMBL11730018 0.97 TSHR (0.50) TSHRLMNACYP3A4MAPK1TDP1
Hydrochloric Acid SCHEMBL9269217 0.97 TSHR (0.50) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL6156142 0.85 TSHR (0.46) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL4475144 0.85 TSHR (0.50) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL545083 0.83 TSHR (0.50) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL30318973 0.83 TSHR (0.50) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL6683028 0.80 KCNN4 (0.46) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL11049028 0.80 KCNN4 (0.58) TSHRLMNACYP3A4MAPK1TDP1
SCHEMBL9409624 0.80 KCNN4 (0.46) TSHRLMNACYP3A4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-118812350-A Method for synthesizing m-chlorobenzoyl chloride from m-chlorotoluene 江苏聚由新材料科技有限公司 2024-10-22 CN claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
CN-113971837-B Knowledge-based dynamic graph neural sign language translation method based on multi-modal feature fusion 厦门大学 2024-08-20 CN claimed
CN-117504735-A Equipment and method for co-producing acyl chloride from o-chlorobenzaldehyde 常州新东化工发展有限公司 2024-02-06 CN claimed
CN-115819646-A Hydroximic acid modified macroporous iminodiacetic acid chelating resin and preparation method thereof 广东省科学院资源利用与稀土开发研究所 2023-03-21 CN claimed
CN-112710760-B Method for determining chlorine organic pollutants in textile solid waste through multi-method combination 中华人民共和国乌鲁木齐海关 2022-11-25 CN claimed
US-20220336811-A1 CATHODE ACTIVE MATERIAL FOR SECONDARY BATTERY COMPRISING CHARGE TRANSFER COMPLEX AND METHOD FOR MANUFACTURING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2022-10-20 US claimed
EP-0558997-A1 Process for reducing the halogen-content of polyhalogenated aromatics BAYER AG (DE) 1993-09-08 EP claimed
US-5091540-A Process for preparing clotrimazole ERREGIERRE INDUSTRIA CHIMICA S.P.A. (IT) 1992-02-25 US claimed
EP-0253836-B1 PREPARATION OF FLUOROAROMATIC COMPOUNDS IN DISPERSION OF POTASSIUM FLUORIDE Mallinckrodt, Inc. (a Delaware corporation) (US) 1990-10-03 EP claimed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO claimed
EP-0018481-B1 PROCESS FOR PRODUCING ALPHA, ALPHA, ALPHA-TRIFLUORO-O-TOLUIC FLUORIDE NIHON NOHYAKU CO., LTD. (JP) 1983-01-12 EP claimed
EP-0010565-B1 PROCESS FOR PREPARING N-TRITYLIMIDAZOLE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-10 EP claimed
EP-0015577-B1 PROCESS FOR PRODUCING 1,1,3,3-TETRAFLUORO-1,3-DIHYDRO-ISOBENZOFURAN NIHON NOHYAKU CO., LTD. (JP) 1982-02-03 EP claimed
EP-0010565-A1 Process for preparing N-tritylimidazole compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-05-14 EP claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
US-4013817-A HALOGENATED AROMATIC HYDROCARBON BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-03-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220336811-A1 CATHODE ACTIVE MATERIAL FOR SECONDARY BATTERY COMPRISING CHARGE TRANSFER COMPLEX AND METHOD FOR MANUFACTURING SAME SCO2, TRMT1, ETFB TSHR 4379/4885LMNA 2848/4885CYP3A4 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.