SCHEMBL545083

SCHEMBL545083

ClC(Cl)(Cl)c1ccccc1C(Cl)(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.50
LMNA P02545 1/20 0.44
KCNN4 O15554 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 4/20 0.33
CYP2A6 P11509 5/20 0.31
ALOX12 P18054 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30318973 1.00 TSHR (0.50) TSHRLMNAKCNN4TDP1CYP3A4
Benzene SCHEMBL21048983 0.96 TSHR (0.56) TSHRLMNAKCNN4TDP1CYP3A4
SCHEMBL6565488 0.87 ALDH1A1 (0.44) TSHRLMNATDP1CYP3A4MAPK1
SCHEMBL11724304 0.85 TSHR (0.39) TSHRLMNAKCNN4TDP1CYP3A4
SCHEMBL197704 0.83 TSHR (0.53) TSHRLMNAKCNN4TDP1CYP3A4
SCHEMBL2046540 0.83 TSHR (0.43) TSHRLMNAKCNN4TDP1CYP3A4
SCHEMBL29617470 0.83 TSHR (0.53) TSHRLMNAKCNN4TDP1CYP3A4
Fluoride SCHEMBL11730018 0.81 TSHR (0.50) TSHRLMNAKCNN4TDP1CYP3A4
Hydrochloric Acid SCHEMBL9269217 0.81 TSHR (0.50) TSHRLMNAKCNN4TDP1CYP3A4
SCHEMBL8728943 0.81 TSHR (0.41) TSHRLMNAKCNN4TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119668028-A Negative photoresist composition, application thereof and imaging method 福建泓光半导体材料有限公司 2025-03-21 CN claimed
CN-118206441-A Preparation method of trifluoromethyl benzoic acid 黑龙江邦普生物科技有限公司 2024-06-18 CN claimed
CN-113307735-B Novel recrystallization process of phthaloyl chloride and bis (trichloromethyl) benzene 江苏方圆芳纶研究院有限公司 2022-11-08 CN claimed
CN-113307735-A Novel recrystallization process of phthaloyl chloride and bis (trichloromethyl) benzene 江苏方圆芳纶研究院有限公司 2021-08-27 CN claimed
CN-112657420-A Spherical phthaloyl chloride particles and preparation method thereof 江苏方圆芳纶研究院有限公司 2021-04-16 CN claimed
EP-3045440-B1 METHOD FOR THE PREPARATION OF TRICHLOROMETHYL-GROUP-SUBSTITUTED BENZENE FININGS CO LTD (CN) 2019-06-12 EP claimed
US-9556090-B2 Method for the preparation of trichloromethyl-group-substituted benzene SHANGHAI FANGLUN NEW MATERIAL TECHNOLOGY CO., LTD. (CN) 2017-01-31 US claimed
EP-3045440-A1 METHOD FOR THE PREPARATION OF TRICHLOROMETHYL-GROUP-SUBSTITUTED BENZENE Shanghai Fanglun New Material Technology Co. Ltd. (CN) 2016-07-20 EP claimed
US-20160152533-A1 METHOD FOR THE PREPARATION OF TRICHLOROMETHYL-GROUP-SUBSTITUTED BENZENE Shanghai Fanglun New Marerial Technology Co., Ltd. (CN) 2016-06-02 US claimed
EP-0953557-B1 Method for producing bis(trifluoromethyl)benzene CENTRAL GLASS CO LTD (JP) 2004-03-31 EP claimed
EP-0250872-A1 Process for the production in continuous of phtalodinitrile CAFFARO S.p.A. Società per l'Industria Chimica ed Elettrochimica (IT) 1988-01-07 EP claimed
US-4500471-A REACTING TRICHLORO-OR TRIBROMOMETHYLBENZOYL HALIDES WITH HYDROGEN FLORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1985-02-19 US claimed
EP-0038223-B1 PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES OCCIDENTAL CHEMICAL CORPORATION (US) 1984-08-08 EP claimed
EP-0038223-A1 Process for the preparation of trifluoromethylbenzoyl halides OCCIDENTAL CHEMICAL CORPORATION (US) 1981-10-21 EP claimed
US-4183873-A WITH HYDROGEN FLUORIDE IN THE PRESENCE OF MOLYBDENUM PENTACHLORIDE CATALYST HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-01-15 US claimed
US-4091017-A FRIEDEL-CRAFTS CATALYSTS, HYDROLYSIS DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-05-23 US claimed
US-4080378-A REACTING A CARBOXYLIC ACID ESTER WITH A TRICHLOROMETHYL SUBSTITUTED AROMATIC COMPOUND IN THE PRESENCE OF A MOLYBDENUM CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-03-21 US claimed
US-4079089-A CONTACTING A BIS/TRICHLOROMETHYL/-BENZENE WITH HYDROGEN FLUORIDE, HALOGEN TRANSFER CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US claimed
US-4056455-A ACTINIC RADIATION, CHLORINATION HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed
US-4013817-A HALOGENATED AROMATIC HYDROCARBON BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-03-22 US claimed