Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921776 | 0.86 | NPC1 (0.40) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL11921787 | 0.78 | LMNA (0.36) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL11925961 | 0.75 | TMPRSS15 (0.35) | — | |
| SCHEMBL11921774 | 0.74 | GAA (0.43) | LMNATSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20365629 | 0.72 | ITGB3 (0.34) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL11921775 | 0.72 | ITGB3 (0.45) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL11921762 | 0.70 | PRSS1 (0.34) | — | |
| SCHEMBL16270512 | 0.67 | CYP1A2 (0.55) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL9420518 | 0.67 | NPC1 (0.67) | NPC1RAB9ALMNATSHRCYP1A2 | |
| SCHEMBL1807523 | 0.67 | NPC1 (0.67) | NPC1RAB9ALMNATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868696-B2 | Amino acid derivatives and absorbable polymers therefrom | Bezwada Biomedial, LLC (US) | 2018-01-16 | — | — | US | disclosed |