Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 15/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212016 | 1.00 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6TAS1R3TAS1R1 | |
| SCHEMBL16220919 | 1.00 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6TAS1R3TAS1R1 | |
| SCHEMBL16371864 | 0.84 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL19775167 | 0.84 | HCRTR1 (0.46) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL17598751 | 0.82 | HCRTR1 (0.52) | HCRTR1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24543387 | 0.79 | ACKR3 (0.42) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL30704818 | 0.79 | ACKR3 (0.42) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL21273819 | 0.79 | ACKR3 (0.42) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL21273811 | 0.79 | ACKR3 (0.42) | HCRTR1ACKR3HDAC6 | |
| SCHEMBL29687045 | 0.79 | ACKR3 (0.42) | HCRTR1ACKR3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2016-03-17 | — | — | US | disclosed |
| EP-2991487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177487-A9 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | disclosed |
| WO-2014177487-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2014-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075653-A1 | NEMATICIDAL N-(PHENYLCYCLOALKYL)CARBOXAMIDES AND N-(PHENYLCYCLOALKYL)THIOCARBOXAMIDES | DNPH1, AADAC, NAAA | HCRTR1 1170/4885ACKR3 4363/4885HDAC6 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.