Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.49 |
| ▸ | GABRD | O14764 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.49 |
| ▸ | GABRE | P78334 | 3/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517816 | 0.81 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25862554 | 0.78 | DYRK1A (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13906113 | 0.78 | ADORA2A (0.44) | ADORA2AADORA2BDYRK1APIM1MAP2K4 | |
| SCHEMBL7920977 | 0.77 | ADORA2A (0.47) | ADORA2AADORA2BDYRK1APIM1 | |
| SCHEMBL16517106 | 0.76 | PRKAG1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16516994 | 0.74 | KDM4E (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24121819 | 0.74 | ADORA2A (0.44) | ADORA2AADORA2BDYRK1APIM1MAP2K4 | |
| SCHEMBL19965414 | 0.74 | ADORA2A (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17514109 | 0.72 | GABRA1 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17683153 | 0.72 | ADORA2A (0.50) | ADORA2AADORA2BCHEK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011628-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-18 | — | — | WO | disclosed |