Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780914 | 1.00 | PPARG (0.63) | PPARGPPARATAS1R3TAS1R1MMP1 | |
| SCHEMBL19780917 | 0.84 | PPARG (0.71) | PPARGPPARATAS1R3TAS1R1MMP1 | |
| SCHEMBL19781294 | 0.80 | PPARG (0.64) | PPARGPPARAMMP1TP53TSHR | |
| SCHEMBL19781324 | 0.78 | PPARG (1.00) | PPARGPPARAMMP1TP53TSHR | |
| SCHEMBL19781328 | 0.78 | PPARG (1.00) | PPARGPPARAMMP1TP53TSHR | |
| SCHEMBL2310923 | 0.77 | PPARG (0.70) | PPARGPPARATAS1R3TAS1R1TP53 | |
| SCHEMBL19781423 | 0.77 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL19780890 | 0.76 | PPARG (0.60) | PPARGPPARATAS1R3TAS1R1MMP1 | |
| SCHEMBL2316696 | 0.76 | TAS1R3 (0.65) | PPARGPPARATAS1R3TAS1R1TP53 | |
| SCHEMBL13366183 | 0.75 | TAS1R3 (0.55) | PPARGTAS1R3TAS1R1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |