Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781406 | 0.90 | CA1 (0.59) | PPARGHRH3PPARAALDH1A1CYP1A2 | |
| SCHEMBL9830755 | 0.87 | CA1 (0.62) | HRH3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19780917 | 0.80 | PPARG (0.71) | PPARGPPARA | |
| SCHEMBL19781294 | 0.80 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL15036987 | 0.79 | PPARG (0.45) | PPARGPPARAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22449154 | 0.79 | PPARG (0.45) | PPARGPPARAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15037344 | 0.79 | PPARG (0.45) | PPARGPPARAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL404703 | 0.79 | CA1 (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C19CA1 | |
| SCHEMBL19781396 | 0.79 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL19780919 | 0.77 | PPARG (0.63) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |