SCHEMBL4445207

SCHEMBL4445207

CC(C)c1ccc(Cl)cc1.[MgH2]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.62
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.50
MAPK1 P28482 2/20 0.50
HIF1A Q16665 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CYP2A6 P11509 1/20 0.50
POLB P06746 1/20 0.50
TP53 P04637 1/20 0.48
HPGD P15428 1/20 0.48
TYR P14679 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
BRD4 O60885 1/20 0.44
CYP19A1 P11511 3/20 0.44
IDO1 P14902 2/20 0.44
TDO2 P48775 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197810 0.97 ADRB2 (0.65) ADRB2LMNATSHRMAPK1HIF1A
Hydrogen Sulfide SCHEMBL28263778 0.94 ADRB2 (0.62) ADRB2LMNATSHRMAPK1HIF1A
SCHEMBL30720007 0.94 ADRB2 (0.62) ADRB2LMNATSHRMAPK1HIF1A
Hydrochloric Acid SCHEMBL28767407 0.94 ADRB2 (0.62) ADRB2LMNATSHRMAPK1HIF1A
Hydrogen Peroxide SCHEMBL10348371 0.91 ADRB2 (0.59) ADRB2LMNATSHRMAPK1HIF1A
SCHEMBL12591826 0.88 ADRB2 (0.56) ADRB2LMNATSHRMAPK1HIF1A
SCHEMBL104124 0.83 TYR (0.58) ADRB2LMNAMAPK1HIF1ATP53
SCHEMBL24616595 0.82 ADRB2 (0.50) ADRB2LMNATSHRMAPK1HIF1A
SCHEMBL8297380 0.82 MAOA (0.60) ADRB2TSHRMAPK1HIF1ATDP1
SCHEMBL9876894 0.82 ADRB2 (0.50) ADRB2LMNATSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 US disclosed
EP-3719099-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2022-09-14 EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 US disclosed
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-05-23 US disclosed
US-10230060-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-03-12 US disclosed
EP-3327100-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2018-05-30 EP disclosed
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-24 US disclosed
US-20150357588-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2015-12-10 US disclosed
US-9142786-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 US disclosed
US-20130248832-A1 Phosphorescent Materials UNIVERSAL DISPLAY CORPORATION 2013-09-26 US disclosed
EP-2121871-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2013-08-14 EP disclosed
US-8431243-B2 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2013-04-30 US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 EP disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 ADRB2 1062/4885LMNA 4175/4885TSHR 4636/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 ADRB2 788/4885LMNA 3740/4885TSHR 940/4885
US-20180145267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, ICMT ADRB2 4509/4885LMNA 2327/4885TSHR 4512/4885
US-20150357588-A1 PHOSPHORESCENT MATERIALS PPA1, PIEZO1, MTAP ADRB2 4813/4885LMNA 2124/4885TSHR 4479/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 ADRB2 788/4885LMNA 3740/4885TSHR 940/4885
US-10230060-B2 Organic electroluminescent materials and devices RUVBL2, OR10J3, EML4 ADRB2 566/4885LMNA 3521/4885TSHR 1072/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 ADRB2 667/4885LMNA 4127/4885TSHR 435/4885
US-20190157576-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PIEZO1, ORAI2, PORCN ADRB2 4410/4885LMNA 1976/4885TSHR 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.