Sugi Predict

Sugi Predict / Compounds / SCHEMBL19781069

SCHEMBL19781069

SCHEMBL19781069

NCCCCCNC(=O)C(F)(F)F

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.79
▸ KMT2A Q03164 1/20 0.79
▸ ALDH1A1 P00352 2/20 0.75
▸ SMN1; SMN2 Q16637 2/20 0.75
▸ POLB P06746 1/20 0.75
▸ EPHX1 P07099 1/20 0.66
▸ CA3 P07451 2/20 0.64
▸ CA5A P35218 2/20 0.64
▸ CA5B Q9Y2D0 2/20 0.64
▸ CA14 Q9ULX7 2/20 0.64
▸ CA12 O43570 1/20 0.64
▸ CA2 P00918 1/20 0.64
▸ CA4 P22748 1/20 0.64
▸ CA6 P23280 1/20 0.64
▸ CA7 P43166 1/20 0.64
▸ CA9 Q16790 1/20 0.64
▸ PAOX Q6QHF9 2/20 0.55
▸ HDAC6 Q9UBN7 1/20 0.50
▸ MAOA P21397 1/20 0.44
▸ MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5367616 1.00 MEN1 (0.79) MEN1KMT2AALDH1A1SMN1; SMN2POLB
Hydrochloric Acid SCHEMBL28974271 0.98 MEN1 (0.76) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL6490885 0.98 ALDH1A1 (0.78) MEN1KMT2AALDH1A1SMN1; SMN2POLB
Hydrochloric Acid SCHEMBL29241679 0.96 SMN1; SMN2 (0.75) MEN1KMT2AALDH1A1SMN1; SMN2POLB
Trifluoroacetic Acid SCHEMBL30387588 0.94 MEN1 (0.70) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL3149189 0.91 ALDH1A1 (0.74) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL11981741 0.90 CA5A (0.81) MEN1KMT2AALDH1A1SMN1; SMN2POLB
Hydrochloric Acid SCHEMBL29241548 0.89 SMN1; SMN2 (0.71) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL29982917 0.89 MEN1 (1.00) MEN1KMT2AALDH1A1SMN1; SMN2POLB
SCHEMBL27889238 0.87 ALDH1A1 (1.00) MEN1KMT2AALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12071662-B2 Short pendant arm linkers for nucleotides in sequencing applications ILLUMINA CAMBRIDGE LIMITED (GB) 2024-08-27 — — US disclosed
CN-111094315-B Short overhang linker for nucleotides in sequencing applications 伊鲁米纳剑桥有限公司 2024-04-09 — — CN disclosed
US-20230348968-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2023-11-02 — — US disclosed
US-11655502-B2 Short pendant arm linkers for nucleotides in sequencing applications ILLUMINA CAMBRIDGE LIMITED (GB) 2023-05-23 — — US disclosed
US-20210230687-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2021-07-29 — — US disclosed
US-11001888-B2 Short pendant arm linkers for nucleotides in sequencing applications ILLUMINA CAMBRIDGE LIMITED (GB) 2021-05-11 — — US disclosed
US-10781175-B2 Solid supports and phosphoramidite building blocks for oligonucleotide conjugates AM CHEMICALS LLC (US) 2020-09-22 — — US disclosed
EP-3652191-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS Illumina Cambridge Limited (GB) 2020-05-20 — — EP disclosed
CN-111094315-A Short pendant arm linkers for nucleotides in sequencing applications 伊鲁米纳剑桥有限公司 2020-05-01 — — CN disclosed
US-20200131569-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2020-04-30 — — US disclosed
WO-2019012080-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LTD (GB) 2019-01-17 — — WO disclosed
US-20190017111-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS ILLUMINA CAMBRIDGE LIMITED (GB) 2019-01-17 — — US disclosed
US-20180016232-A1 SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES AM CHEMICALS LLC (US) 2018-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10781175-B2 Solid supports and phosphoramidite building blocks for oligonucleotide conjugates NCL, PAICS, RTCB MEN1 2389/4885KMT2A 1607/4885ALDH1A1 4559/4885
US-20230348968-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-20210230687-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-20200131569-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-11001888-B2 Short pendant arm linkers for nucleotides in sequencing applications POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-11655502-B2 Short pendant arm linkers for nucleotides in sequencing applications POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-20190017111-A1 SHORT PENDANT ARM LINKERS FOR NUCLEOTIDES IN SEQUENCING APPLICATIONS POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-12071662-B2 Short pendant arm linkers for nucleotides in sequencing applications POLRMT, POLM, POLN MEN1 1987/4885KMT2A 2735/4885ALDH1A1 2931/4885
US-20180016232-A1 SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES NCL, PAICS, RTCB MEN1 2389/4885KMT2A 1607/4885ALDH1A1 4559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.