Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.57 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417071 | 1.00 | KMT2A (0.64) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL14195921 | 0.91 | NPC1 (0.55) | KMT2AALDH1A1MEN1LMNAADAM17 | |
| SCHEMBL404406 | 0.91 | NPC1 (0.55) | KMT2AALDH1A1MEN1LMNAADAM17 | |
| SCHEMBL5445989 | 0.88 | ADAM17 (0.52) | KMT2AALDH1A1ADAM17HDAC1HDAC3 | |
| SCHEMBL1912090 | 0.88 | PPARG (0.58) | KMT2AALDH1A1MEN1LMNAPPARG | |
| SCHEMBL399472 | 0.88 | ADAM17 (0.52) | KMT2AALDH1A1ADAM17HDAC1HDAC3 | |
| SCHEMBL1105659 | 0.88 | HDAC1 (0.59) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL7677634 | 0.85 | ALDH1A1 (0.62) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL7677630 | 0.85 | ALDH1A1 (0.62) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL1168553 | 0.84 | SLC1A2 (0.66) | KMT2AALDH1A1MEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |