Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.56 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677630 | 1.00 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL7417071 | 0.85 | KMT2A (0.64) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL19781296 | 0.85 | KMT2A (0.64) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL14318468 | 0.83 | HPGDS (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL15833197 | 0.83 | HPGDS (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL19939555 | 0.83 | HPGDS (0.61) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL1168553 | 0.82 | SLC1A2 (0.66) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9462009 | 0.82 | SLC1A2 (0.66) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL1168551 | 0.82 | SLC1A2 (0.66) | ALDH1A1KMT2AMEN1LMNAHTT | |
| SCHEMBL9829100 | 0.82 | KMT2A (0.61) | ALDH1A1KMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |