Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.65 |
| ▸ | PPARA | Q07869 | 1/20 | 0.65 |
| ▸ | ACACB | O00763 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781398 | 0.87 | ITGB3 (0.72) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL9716935 | 0.86 | PPARG (0.60) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL19781294 | 0.84 | PPARG (0.64) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL11043905 | 0.83 | ITGB3 (0.69) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL11043906 | 0.83 | ITGB3 (0.69) | PPARGPPARARAB9ANPC1MEN1 | |
| SCHEMBL1123162 | 0.83 | ACACB (0.67) | ACACBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL19781304 | 0.80 | PPARG (0.74) | PPARGPPARAPLK1TP53TSHR | |
| SCHEMBL19780924 | 0.79 | PPARG (1.00) | PPARGPPARAPLK1TP53TSHR | |
| SCHEMBL19781325 | 0.79 | PPARG (1.00) | PPARGPPARAPLK1TP53TSHR | |
| SCHEMBL22756205 | 0.79 | PPARG (0.52) | PPARGPPARAACACBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |