Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.72 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.67 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | PPARA | Q07869 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043906 | 0.96 | ITGB3 (0.69) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL11043905 | 0.96 | ITGB3 (0.69) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL1123184 | 0.91 | GPR132 (0.67) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL12029320 | 0.91 | ITGB3 (0.69) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL19781294 | 0.90 | PPARG (0.64) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL15100180 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL12029291 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL4369225 | 0.88 | ITGB3 (0.68) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL9716935 | 0.87 | PPARG (0.60) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL19781298 | 0.87 | PPARG (0.65) | ITGB3ITGA2BPPARGPPARARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |