SCHEMBL19781335

SCHEMBL19781335

Fc1cc(C#CSI)ccc1Cl

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22853322 0.82 GRM5 (0.43) FFAR1FFAR4GRM5
SCHEMBL19781337 0.82 PYGL (0.40)
SCHEMBL8771367 0.75 CYP1A1 (0.39) FFAR1FFAR4RAPGEF4GRM5
SCHEMBL19808998 0.75 FFAR1 (0.36) FFAR1FFAR4RAPGEF4GRM5
SCHEMBL22666661 0.72 APP (0.36)
SCHEMBL22163459 0.71 KCNH2 (0.39) GRM5
SCHEMBL21474350 0.71 KDM1A (0.31)
SCHEMBL20537367 0.70 SLC6A4 (0.36) FFAR1FFAR4RAPGEF4GRM5
SCHEMBL19781334 0.70 RAPGEF4 (0.33) FFAR1FFAR4RAPGEF4GRM5
SCHEMBL16955681 0.70 RAPGEF4 (0.34) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018011094-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2018-01-18 WO disclosed