SCHEMBL19781336

SCHEMBL19781336

C[Si](C)(C)C#Cc1cc(F)c(Cl)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19781318 0.90
SCHEMBL22469640 0.80 CCR1 (0.31)
SCHEMBL21474353 0.79
SCHEMBL7526965 0.78 LOX (0.31)
SCHEMBL19781334 0.78 RAPGEF4 (0.33)
SCHEMBL24132797 0.76 LOX (0.30)
SCHEMBL19677742 0.76 HDAC1 (0.31)
SCHEMBL20929147 0.75 LOX (0.32)
SCHEMBL20929233 0.75 ALDH1A1 (0.41)
SCHEMBL19781323 0.75 KDM1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563119-A α-D- galactoside the inhibitor of galactose agglutinin 格莱克特生物技术公司 2019-04-02 CN disclosed
WO-2018011094-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2018-01-18 WO disclosed