Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 3/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781294 | 0.83 | PPARG (0.64) | PPARGMMP2PPARAITGB1ITGA4 | |
| SCHEMBL19781423 | 0.79 | PPARG (0.58) | PPARGPPARA | |
| SCHEMBL19780917 | 0.78 | PPARG (0.71) | PPARGPPARA | |
| SCHEMBL19780890 | 0.76 | PPARG (0.60) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL19781398 | 0.74 | ITGB3 (0.72) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL19780919 | 0.73 | PPARG (0.63) | PPARGPPARATAOK3TAOK1 | |
| SCHEMBL19780914 | 0.73 | PPARG (0.63) | PPARGPPARATAOK3TAOK1 | |
| SCHEMBL19781324 | 0.72 | PPARG (1.00) | PPARGPPARATAOK3TAOK1 | |
| SCHEMBL19781328 | 0.72 | PPARG (1.00) | PPARGPPARATAOK3TAOK1 | |
| SCHEMBL19781298 | 0.71 | PPARG (0.65) | PPARGPPARATAOK3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011230-A1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONISTS, METHOD OF PREPARATION AND USES THEREOF | UNIVERSITE D'AIX-MARSEILLE (FR) | 2018-01-18 | — | — | WO | disclosed |