Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781517 | 0.82 | SAT1 (0.33) | SAT1GNAI3GNAO1GNAI1 | |
| SCHEMBL19781756 | 0.81 | — | — | |
| SCHEMBL19782060 | 0.80 | GNAI3 (0.33) | SAT1GNAI3GNAO1GNAI1 | |
| SCHEMBL19780085 | 0.78 | SAT1 (0.39) | SAT1GNAI3GNAO1GNAI1POLB | |
| SCHEMBL19609421 | 0.78 | GNAI3 (0.49) | SAT1GNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL19782059 | 0.77 | ATM (0.38) | SAT1KDM4ETDP1 | |
| SCHEMBL19779638 | 0.77 | SAT1 (0.34) | SAT1GNAI3GNAO1GNAI1 | |
| SCHEMBL19782073 | 0.77 | SAT1 (0.38) | SAT1GNAI3GNAO1GNAI1 | |
| SCHEMBL19780082 | 0.77 | GUSB (0.53) | GNAI3GNAO1GNAI1 | |
| SCHEMBL24922554 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013676-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-01-18 | — | — | WO | disclosed |