Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HOGA1 | Q86XE5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SAT1 | P21673 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19780181 | 0.79 | HRH3 (0.40) | ATMALDH1A1TSHRNPSR1 | |
| SCHEMBL2773094 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4349285 | 0.77 | SAT1 (0.47) | ATMALDH1A1TSHRNPSR1HOGA1 | |
| SCHEMBL19781522 | 0.77 | SAT1 (0.38) | KDM4ETDP1SAT1 | |
| SCHEMBL19781517 | 0.77 | SAT1 (0.33) | BRD4SAT1 | |
| SCHEMBL19782060 | 0.75 | GNAI3 (0.33) | SAT1 | |
| SCHEMBL19780085 | 0.73 | SAT1 (0.39) | KDM4EHOGA1SAT1 | |
| SCHEMBL7946281 | 0.73 | ADH1B (0.42) | ATMALDH1A1TSHRNPSR1KDM4E | |
| SCHEMBL19782073 | 0.72 | SAT1 (0.38) | SAT1 | |
| SCHEMBL24922554 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013676-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-01-18 | — | — | WO | disclosed |