SCHEMBL19782060

SCHEMBL19782060

CN1CC(CNCCF)C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
SAT1 P21673 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19782073 0.88 SAT1 (0.38) GNAI3GNAO1GNAI1SAT1
SCHEMBL19781517 0.80 SAT1 (0.33) GNAI3GNAO1GNAI1SAT1
SCHEMBL19781522 0.80 SAT1 (0.38) GNAI3GNAO1GNAI1SAT1
SCHEMBL19779739 0.78
SCHEMBL19780085 0.77 SAT1 (0.39) GNAI3GNAO1GNAI1SAT1
SCHEMBL19782059 0.75 ATM (0.38) SAT1
SCHEMBL24922554 0.75
SCHEMBL19781756 0.75
SCHEMBL24832948 0.74
SCHEMBL10864747 0.69 GNAI3 (0.50) GNAI3GNAO1GNAI1SAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018013676-A1 SOMATOSTATIN MODULATORS AND USES THEREOF Crinetics Pharmaceuticals, Inc. (US) 2018-01-18 WO disclosed