Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781533 | 0.89 | MAPT (0.45) | ACP1MAPTGLATP53CSF1R | |
| SCHEMBL19781139 | 0.86 | ACP1 (0.41) | ACP1MAPTTP53NPC1SYK | |
| SCHEMBL19781791 | 0.85 | ACP1 (0.40) | ACP1MAPTGLATP53P2RX3 | |
| SCHEMBL19781774 | 0.78 | ACP1 (0.45) | ACP1MAPTGLATP53CSF1R | |
| SCHEMBL2723103 | 0.71 | GLA (0.57) | MAPTGLATP53P2RX3NPC1 | |
| SCHEMBL4215577 | 0.69 | AKR1C3 (0.52) | MAPTCSF1RKMT2ASMN1; SMN2RXRA | |
| SCHEMBL197284 | 0.69 | ALDH1A3 (0.56) | GLAERN1KMT2AACACBACACA | |
| SCHEMBL24022572 | 0.67 | LRRK2 (0.47) | MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL14817450 | 0.67 | ACACB (0.59) | KMT2AACACBACACAALDH1A3POLB | |
| SCHEMBL141942 | 0.67 | P2RX3 (0.42) | ACP1MAPTTP53P2RX3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |