Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781832 | 0.69 | NOS1 (0.42) | MAPK1HSD17B10KDM4ENOS1LMNA | |
| SCHEMBL14699733 | 0.69 | HSD17B10 (0.41) | TLR8TLR7MAPK1HSD17B10KDM4E | |
| SCHEMBL5501897 | 0.68 | TLR8 (0.47) | TLR8TLR7MAPK1HSD17B10KDM4E | |
| SCHEMBL77254 | 0.67 | HSD17B10 (0.39) | TLR8TLR7MAPK1HSD17B10KDM4E | |
| SCHEMBL19267555 | 0.67 | HSD17B10 (0.39) | TLR8TLR7MAPK1HSD17B10KDM4E | |
| SCHEMBL19229127 | 0.65 | MAPK1 (0.35) | TLR8TLR7MAPK1HSD17B10KDM4E | |
| SCHEMBL17339833 | 0.65 | HSD17B10 (0.38) | TLR8TLR7MAPK1HSD17B10KDM4E | |
| SCHEMBL11563145 | 0.64 | TLR8 (0.33) | TLR8TLR7 | |
| SCHEMBL2616828 | 0.64 | — | — | |
| SCHEMBL19626330 | 0.63 | HSD17B10 (0.37) | TLR8TLR7MAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013389-A1 | BLUE-EXCITABLE WATER-SOLVATED POLYMERIC DYES | BECTON, DICKINSON AND COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |