SCHEMBL77254

SCHEMBL77254

Cc1nc2c(C)c(C)c(C)c(C)c2s1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
TLR8 Q9NR97 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 1/20 0.31
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14699733 0.92 HSD17B10 (0.41) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL19267555 0.89 HSD17B10 (0.39) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL21166579 0.80 KDM4E (0.35) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL19821654 0.80 KDM4E (0.33) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL19626331 0.77 KDM4E (0.36) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL19626332 0.77 KDM4E (0.36) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL17934028 0.75 TLR8 (0.53) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL9148321 0.74
SCHEMBL12109854 0.74 HTT (0.46) HSD17B10KDM4EMAPK1NPC1RAB9A
SCHEMBL23236828 0.70 KDM4E (0.35) HSD17B10KDM4EMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-11758809-B2 Compound, display panel, and display apparatus Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-09-12 US disclosed
US-11751474-B2 Compound and organic light emitting display device WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-09-05 US disclosed
US-20230193039-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING NORTHWESTERN UNIVERSITY (US) 2023-06-22 US disclosed
US-10011573-B2 Human androgen receptor DNA-binding domain (DBD) compounds as therapeutics and methods for their use THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2018-07-03 US disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180040834-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2018-02-08 US disclosed
US-9882141-B2 Pyrene-based compound and organic light-emitting diode including the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-01-30 US disclosed
US-20170349675-A1 NEW POLYOLEFIN CATALYST AND USE THEREOF SHANGHAI CHEMRUN CO. LTD. (CN) 2017-12-07 US disclosed
US-20170349675-A1 NEW POLYOLEFIN CATALYST AND USE THEREOF SHANGHAI CHEMRUN CO. LTD. (CN) 2017-12-07 US disclosed
US-20090258875-A1 Fungicide Hydroximoyl-Tetrazole Derivatives BAYER CROPSCIENCE AG (DE) 2009-10-15 US disclosed
US-20090247672-A1 INK COMPOSITION, INK FOR INKJET RECORDING AND INK SET USING THE INK FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246379-A1 Method for forming ink jet image FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090192196-A1 Fungicide hydroximoyl-tetrazole derivatives BAYER CROPSCIENCE AG (DE) 2009-07-30 US disclosed
US-7527683-B2 Ink for ink-jet recording, ink set, and ink-jet recording method FUJIFILM CORPORATION (JP) 2009-05-05 US disclosed
US-20090045725-A1 POLYARYLENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-19 US disclosed
US-20090043081-A1 INK JET RECORDING SET AND INK JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-02-12 US disclosed
US-20080061673-A1 Solution Composition And Polymer Light-Emitting Device SUMITOMO CHEMICAL CO., LTD. (JP) 2008-03-13 US disclosed
US-20080011191-A1 Novel Azo Compound or Salt, Ink Composition Comprising Such Azo Compound, and Colored Article NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-01-17 US disclosed
US-20070254240-A1 Dye-containing negative curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2007-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230193039-A1 SELENIUM-CONTAINING ANALOGUES OF PHEOMELANIN AND RELATED MATERIALS AND METHODS OF MAKING SELENOI, SCLY, SELP HSD17B10 2223/4885KDM4E 3403/4885MAPK1 2132/4885
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, NR2E3, ERG HSD17B10 1154/4885KDM4E 3633/4885MAPK1 3742/4885
US-20180040834-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A1 HSD17B10 84/4885KDM4E 4276/4885MAPK1 2533/4885
US-20090192196-A1 Fungicide hydroximoyl-tetrazole derivatives HAAO, HAO1, CYP51A1 HSD17B10 269/4885KDM4E 760/4885MAPK1 2712/4885
US-10011573-B2 Human androgen receptor DNA-binding domain (DBD) compounds as therapeutics and methods for their use AR, SHBG, BRCA1 HSD17B10 219/4885KDM4E 1638/4885MAPK1 3165/4885
US-20170349675-A1 NEW POLYOLEFIN CATALYST AND USE THEREOF NOTUM, WEE1, FAR1 HSD17B10 472/4885KDM4E 4527/4885MAPK1 3123/4885
US-20090258875-A1 Fungicide Hydroximoyl-Tetrazole Derivatives HAAO, CYP51A1, CYP8B1 HSD17B10 296/4885KDM4E 648/4885MAPK1 2725/4885
US-11785841-B2 Compound, display panel and display apparatus C1S, CDK20, CEP170 HSD17B10 462/4885KDM4E 3873/4885MAPK1 3061/4885
US-20080011191-A1 Novel Azo Compound or Salt, Ink Composition Comprising Such Azo Compound, and Colored Article RB1, JAK1, IK HSD17B10 2228/4885KDM4E 150/4885MAPK1 79/4885
US-11751474-B2 Compound and organic light emitting display device L1CAM, C1S, CCNE2 HSD17B10 3544/4885KDM4E 3712/4885MAPK1 2680/4885
US-11758809-B2 Compound, display panel, and display apparatus C1S, C3AR1, DRD3 HSD17B10 1782/4885KDM4E 4098/4885MAPK1 2431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.