Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19267555 | 0.92 | HSD17B10 (0.39) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL77254 | 0.92 | HSD17B10 (0.39) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL21166579 | 0.88 | KDM4E (0.35) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL19626332 | 0.79 | KDM4E (0.36) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL19626331 | 0.79 | KDM4E (0.36) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL17934028 | 0.78 | TLR8 (0.53) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL19821654 | 0.78 | KDM4E (0.33) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL12109854 | 0.76 | HTT (0.46) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL23236828 | 0.72 | KDM4E (0.35) | HSD17B10MAPK1KDM4ENPC1RAB9A | |
| SCHEMBL17339833 | 0.72 | HSD17B10 (0.38) | HSD17B10MAPK1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
| US-20170069845-A1 | ORGANIC SEMICONDUCTOR MATERIAL | TOYOBO CO., LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| US-20160369045-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | CORNING INC (US) | 2016-12-22 | — | — | US | disclosed |
| US-20150065722-A1 | FUSED THIOPHENE DITIN MONOMERS | CORNING INCORPORATED | 2015-03-05 | — | — | US | disclosed |
| US-20150045560-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | CORNING INCORPORATED | 2015-02-12 | — | — | US | disclosed |
| EP-2008318-B1 | METHOD FOR PREPARING DOPED ORGANIC SEMICONDUCTOR MATERIALS | NOVALED AG (DE) | 2013-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065722-A1 | FUSED THIOPHENE DITIN MONOMERS | TTL, THEM6, ITK | HSD17B10 2958/4885MAPK1 3561/4885KDM4E 1273/4885 |
| US-20170069845-A1 | ORGANIC SEMICONDUCTOR MATERIAL | TST, TH, TPR | HSD17B10 1674/4885MAPK1 3013/4885KDM4E 3605/4885 |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | HSD17B10 2640/4885MAPK1 3214/4885KDM4E 2444/4885 |
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | HSD17B10 1714/4885MAPK1 3641/4885KDM4E 2858/4885 |
| US-20150045560-A1 | NOVEL FUSED NAPHTHALENE CYCLOHETERO RING COMPOUNDS, AND METHODS AND USES THEREOF | FDPS, PPOX, DHPS | HSD17B10 794/4885MAPK1 4617/4885KDM4E 2456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.