Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16778195 | 0.84 | CYP4F2 (0.44) | SMN1; SMN2LMNAALDH1A1KDM4EGAA | |
| SCHEMBL38655175 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL31292217 | 0.83 | KDM4E (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30760421 | 0.80 | MAPT (0.48) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL31716064 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23214039 | 0.80 | MAPT (0.48) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL24614557 | 0.80 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12764804 | 0.79 | KMT2A (0.48) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL19874265 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ALMNATSHR | |
| SCHEMBL17765273 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916777-B | ATX inhibitor and preparation method and application thereof | 苏州爱科百发生物医药技术有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20230295159-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SUZHOU ARK BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295159-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SUZHOU ARK BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295159-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SUZHOU ARK BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| EP-4180430-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Ark Biopharmaceutical Co., Ltd (CN) | 2023-05-17 | — | — | EP | disclosed |
| EP-4180430-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Ark Biopharmaceutical Co., Ltd (CN) | 2023-05-17 | — | — | EP | disclosed |
| CN-115916777-A | ATX inhibitor and preparation method and application thereof | 苏州爱科百发生物医药技术有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022007882-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州爱科百发生物医药技术有限公司 | 2022-01-13 | — | — | WO | disclosed |
| CN-113912600-A | ATX inhibitor and preparation method and application thereof | 苏州爱科百发生物医药技术有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2019-05-23 | — | — | US | disclosed |
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2019-05-23 | — | — | US | disclosed |
| EP-3481809-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | Cadila Healthcare Limited (IN) | 2019-05-15 | — | — | EP | disclosed |
| WO-2018011746-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2018-01-18 | — | — | WO | disclosed |
| WO-2018011746-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | RORC, RORB, RORA | SMN1; SMN2 3885/4885MEN1 4599/4885KMT2A 3541/4885 |
| US-20230295159-A1 | ATX INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ATXN10, GCG, ATXN2L | SMN1; SMN2 585/4885MEN1 579/4885KMT2A 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.