Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ILK | Q13418 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189678 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ILKPDGFRBPDGFRA | |
| SCHEMBL30189744 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ILKPDGFRBPDGFRA | |
| SCHEMBL19783248 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ILKPDGFRBPDGFRA | |
| SCHEMBL20597620 | 0.75 | ALDH1A1 (0.74) | ALDH1A1ILK | |
| SCHEMBL6514749 | 0.72 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL19775976 | 0.71 | ILK (0.40) | ALDH1A1ILKPDGFRBPDGFRA | |
| SCHEMBL21468916 | 0.70 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL29872373 | 0.69 | ALDH1A1 (0.46) | ALDH1A1PDGFRA | |
| SCHEMBL19776248 | 0.68 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL19776328 | 0.68 | ALDH1A1 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, PF4 | ALDH1A1 1618/4885ILK 2829/4885PDGFRB 494/4885 |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, F12 | ALDH1A1 1598/4885ILK 2999/4885PDGFRB 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.