Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189743 | 1.00 | F2RL3 (0.44) | F2RL3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30189939 | 0.81 | ALDH1A1 (0.62) | F2RL3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11151695 | 0.81 | ALDH1A1 (0.62) | F2RL3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19782939 | 0.81 | F2RL3 (0.43) | F2RL3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19782620 | 0.81 | F2RL3 (0.45) | F2RL3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19782618 | 0.79 | F2RL3 (0.44) | F2RL3ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22342076 | 0.79 | ALDH1A1 (0.36) | F2RL3ALDH1A1 | |
| SCHEMBL5419706 | 0.76 | KDM4E (0.52) | F2RL3 | |
| SCHEMBL8334368 | 0.76 | ALDH1A1 (0.63) | ALDH1A1CYP3A4 | |
| SCHEMBL19783817 | 0.76 | CYP1A2 (0.33) | ALDH1A1CYP1A2CYP3A4CYP2C19PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, PF4 | F2RL3 2/4885ALDH1A1 1618/4885CYP1A2 200/4885 |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, F12 | F2RL3 2/4885ALDH1A1 1598/4885CYP1A2 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.