Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707241 | 0.81 | ALDH1A1 (0.66) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8311475 | 0.80 | ALDH1A1 (0.42) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL30626878 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL24603498 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8334374 | 0.78 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL11109860 | 0.78 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL6718517 | 0.78 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL2138941 | 0.77 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL14880926 | 0.76 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL19783358 | 0.76 | F2RL3 (0.44) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041341-B | Quinazoline PAR4 antagonist and medical application thereof | 中国药科大学 | 2025-02-28 | — | — | CN | disclosed |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| US-5888940-A | DESICCATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-30 | — | — | US | disclosed |
| EP-0862569-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997008171-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, PF4 | ALDH1A1 1618/4885RAB9A 667/4885SMN1; SMN2 3677/4885 |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, F12 | ALDH1A1 1598/4885RAB9A 748/4885SMN1; SMN2 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.