Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7175027 | 0.83 | PNMT (0.33) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8383536 | 0.82 | NPC1 (0.36) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8380992 | 0.80 | NPC1 (0.33) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2806871 | 0.78 | PNMT (0.33) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3390907 | 0.75 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL5351419 | 0.72 | PNMT (0.44) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7945298 | 0.70 | PNMT (0.35) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7265194 | 0.69 | PNMT (0.35) | PNMTNPC1RAB9A | |
| SCHEMBL814589 | 0.69 | PNMT (0.33) | PNMTNPC1RAB9A | |
| SCHEMBL29959766 | 0.69 | PNMT (0.33) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957158-B2 | Impact resistant LLDPE composition and films made thereof | BASELL POLYOLEFINE GMBH (DE) | 2015-02-17 | — | — | US | disclosed |
| US-8846188-B2 | Impact resistant LLDPE composition and films made thereof | Basell Poliolefine GmbH (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-2344551-B1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2014-05-28 | — | — | EP | disclosed |
| EP-2361281-B1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-20110230629-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20110223406-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20110217537-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-08 | — | — | US | disclosed |
| US-20110212315-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110212283-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-01 | — | — | US | disclosed |
| EP-2361281-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | Basell Polyolefine GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |
| EP-2326678-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | Basell Polyolefine GmbH (DE) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010034461-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034508-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |
| WO-2010034463-A1 | IMPACT RESISTANT LLDPE COMPOSITION AND FILMS MADE THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |