Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1978364 | 0.75 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL2806871 | 0.70 | PNMT (0.33) | PNMT | |
| Hydrochloric Acid SCHEMBL5351419 | 0.68 | PNMT (0.44) | PNMT | |
| Hydrochloric Acid SCHEMBL8384507 | 0.68 | NPC1 (0.34) | PNMT | |
| Hydrochloric Acid SCHEMBL8383877 | 0.67 | NPC1 (0.39) | PNMT | |
| Hydrochloric Acid SCHEMBL6693835 | 0.66 | CYP1A2 (0.33) | — | |
| Fluoride Ion SCHEMBL1130432 | 0.65 | PNMT (0.44) | PNMT | |
| Hydrochloric Acid SCHEMBL30132153 | 0.65 | PNMT (0.33) | PNMT | |
| SCHEMBL8151881 | 0.62 | PNMT (0.64) | PNMT | |
| Hydrochloric Acid SCHEMBL6557783 | 0.62 | PNMT (0.42) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621996-B1 | CATALYST SYSTEMS AND PROCESSES FOR USING THE SAME | UNIVATION TECH LLC (US) | 2023-01-18 | — | — | EP | disclosed |
| US-7829495-B2 | Olefin polymerization process with alkyl-substituted metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20050032992-A1 | Olefin polymerization process with alkyl-substituted metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-02-10 | — | — | US | disclosed |
| US-6759499-B1 | POLYMER PRODUCTS HAVING NARROW COMPOSITION DISTRIBUTIONS, LOW MELT INDEX RATIOS, AND, OPTIONALLY, HIGH MELT STRENGTH | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-06 | — | — | US | disclosed |