Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29091577 | 0.86 | TDP1 (0.47) | TDP1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL9799821 | 0.84 | TDP1 (0.62) | TDP1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL13721530 | 0.84 | TDP1 (0.57) | TDP1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL31150399 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1KMT2ATSHRVCAM1 | |
| SCHEMBL521184 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1KMT2ATSHRVCAM1 | |
| SCHEMBL6576154 | 0.81 | TDP1 (0.53) | TDP1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL15722112 | 0.81 | TDP1 (0.42) | TDP1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2549695 | 0.81 | ALDH1A1 (0.50) | TDP1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL19181006 | 0.79 | TDP1 (0.47) | TDP1MAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL1675914 | 0.79 | ALDH1A1 (0.41) | TDP1MAPK1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070871-A1 | PROCESS FOR PREPARATION OF 2-CHLORO-3-FLUORO-4-ALKOXY-ANILINES AND 2-FLUORO-3-CHLOROPHENOL | BAYER AG (DE) | 2026-03-12 | — | — | US | disclosed |
| CN-119451936-A | Process for preparing 2-chloro-3-fluoro-4-alkoxy-aniline and 2-fluoro-3-chlorophenol | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| US-12060347-B2 | Bicyclic heteroaryl substituted compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-13 | — | — | US | disclosed |
| CN-112142567-B | Preparation method of 2-fluoro-3-chlorophenol | 浙江永太科技股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| CN-112142567-A | Preparation method of 2-fluoro-3-chlorophenol | 浙江永太科技股份有限公司 | 2020-12-29 | — | — | CN | disclosed |
| EP-3484878-B1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-19 | — | — | EP | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070871-A1 | PROCESS FOR PREPARATION OF 2-CHLORO-3-FLUORO-4-ALKOXY-ANILINES AND 2-FLUORO-3-CHLOROPHENOL | CYP2E1, CYP1A1, CYP2F1 | TDP1 1312/4885MAPK1 256/4885ALDH1A1 92/4885 |
| US-12060347-B2 | Bicyclic heteroaryl substituted compounds | F2, F2RL3, F12 | TDP1 227/4885MAPK1 2622/4885ALDH1A1 1598/4885 |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, PF4 | TDP1 353/4885MAPK1 3368/4885ALDH1A1 1618/4885 |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, F12 | TDP1 227/4885MAPK1 2622/4885ALDH1A1 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.