Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.72 |
| ▸ | CCND1 | P24385 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 2/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.54 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582936 | 1.00 | CDK4 (0.72) | CDK4CCND1KMT2ALMNATERT | |
| SCHEMBL1269116 | 0.98 | CDK4 (0.71) | CDK4CCND1KMT2ALMNATERT | |
| SCHEMBL29560163 | 0.94 | CDK4 (0.68) | CDK4CCND1KMT2ALMNATERT | |
| SCHEMBL1967792 | 0.94 | CDK4 (0.68) | CDK4CCND1KMT2ALMNATERT | |
| SCHEMBL29684637 | 0.87 | LMNA (0.73) | CDK4CCND1KMT2ALMNATERT | |
| SCHEMBL526317 | 0.87 | LMNA (0.73) | CDK4CCND1KMT2ALMNATERT | |
| SCHEMBL6154591 | 0.84 | CDK4 (0.66) | CDK4CCND1LMNAMAPK1MTNR1A | |
| SCHEMBL6155367 | 0.84 | CDK4 (0.66) | CDK4CCND1LMNAMAPK1MTNR1A | |
| SCHEMBL24398975 | 0.80 | CDK4 (0.82) | CDK4CCND1KMT2ALMNADRD2 | |
| SCHEMBL1293253 | 0.80 | CDK4 (0.82) | CDK4CCND1KMT2ALMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018010932-A1 | CATALYTIC CARBOXYLATION OF ACTIVATED ALKANES AND/OR OLEFINS | FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ES) | 2018-01-18 | — | — | WO | disclosed |