SCHEMBL1978381

SCHEMBL1978381

NCC(=O)Nc1cccc2c1C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.52
MAPT P10636 3/20 0.52
HPGD P15428 2/20 0.52
MEN1 O00255 2/20 0.52
HTT P42858 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
SMAD3 P84022 1/20 0.52
PRMT1 Q99873 1/20 0.52
ACE2 Q9BYF1 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 2/20 0.50
ALOX12 P18054 2/20 0.50
CYP2C9 P11712 1/20 0.50
ALOX15 P16050 1/20 0.50
BRCA1 P38398 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TYR P14679 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183875 0.89 FTO (0.52) FTOMAPTHPGDMEN1HTT
SCHEMBL11310755 0.89 FTO (0.52) FTOMAPTHPGDMEN1HTT
SCHEMBL7646663 0.89 FTO (0.52) FTOMAPTHPGDMEN1HTT
SCHEMBL9428188 0.86 FTO (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL5149281 0.85 FTO (0.55) FTOMAPTHPGDMEN1HTT
SCHEMBL9427469 0.85 HPGD (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL1254421 0.85 FTO (0.64) FTOMAPTHPGDMEN1HTT
SCHEMBL905219 0.84 FTO (0.47) FTOMAPTHPGDMEN1HTT
SCHEMBL4885766 0.84 FTO (0.47) FTOMAPTHPGDMEN1HTT
SCHEMBL15778575 0.84 FTO (0.47) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4348347-A2 SYSTEM AND METHOD FOR HIGH RESOLUTION 3D NANOFABRICATION Irradiant Technologies Inc. (US) 2024-04-10 EP claimed
WO-2022251546-A2 SYSTEM AND METHOD FOR HIGH RESOLUTION 3D NANOFABRICATION Irradiant Technologies Inc. (US) 2022-12-01 WO claimed
EP-0853680-B1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER EMD BIOSCIENCES INC (US) 2004-03-31 EP claimed
EP-0853680-A4 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER NOVAGEN INC (US) 2000-09-13 EP claimed
EP-0853680-A1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER NOVAGEN, INC. (US) 1998-07-22 EP claimed
WO-1997012994-A1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER NOVAGEN, INC. (US) 1997-04-10 WO claimed
US-20220389478-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR ORYZON GENOMICS SA (ES) 2022-12-08 US disclosed
US-11034991-B2 Methods to determine KDM1A target engagement and chemoprobes useful therefor ORYZON GENOMICS S.A. (ES) 2021-06-15 US disclosed
US-10736943-B2 Silk microspheres for encapsulation and controlled release TRUSTEES OF TUFTS COLLEGE (US) 2020-08-11 US disclosed
US-20190085372-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR ORYZON GENOMICS SA (ES) 2019-03-21 US disclosed
EP-3430015-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR Oryzon Genomics, S.A. (ES) 2019-01-23 EP disclosed
WO-2017158136-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR ORYZON GENOMICS, S.A. (ES) 2017-09-21 WO disclosed
CN-107007835-A Carry Prussian blue targeted nano compound and preparation method thereof 重庆医科大学 2017-08-04 CN disclosed
EP-0689684-A1 CHEMICAL FUNCTIONALIZATION OF POLYMERS THE STATE OF OREGON acting by and through THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 1996-01-03 EP disclosed
US-5464746-A Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives ABBOTT LABORATORIES (US) 1995-11-07 US disclosed
WO-1995009239-A2 PRODUCTION, PURIFICATION, CLEAVAGE AND USE OF FUSION PEPTIDES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1995-04-06 WO disclosed
WO-1995003296-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LABORATORIES (US) 1995-02-02 WO disclosed
EP-0623174-A1 HOMOCYSTEINE ASSAY. COCKBAIN JULIAN R M (GB) 1994-11-09 EP disclosed
WO-1994022053-A1 CHEMICAL FUNCTIONALIZATION OF POLYMERS THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 1994-09-29 WO disclosed
WO-1993015220-A1 HOMOCYSTEINE ASSAY AXIS BIOCHEMICALS AS (NO) 1993-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389478-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR KDM1B, KDM1A, KDM7A FTO 778/4885MAPT 4545/4885HPGD 3810/4885
US-20190085372-A1 METHODS TO DETERMINE KDM1A TARGET ENGAGEMENT AND CHEMOPROBES USEFUL THEREFOR KDM1B, KDM1A, KDM7A FTO 778/4885MAPT 4545/4885HPGD 3810/4885
US-11034991-B2 Methods to determine KDM1A target engagement and chemoprobes useful therefor KDM1B, KDM1A, KDM7A FTO 778/4885MAPT 4545/4885HPGD 3810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.