Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310755 | 0.89 | FTO (0.52) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL183875 | 0.89 | FTO (0.52) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL1978381 | 0.89 | FTO (0.52) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL9428188 | 0.86 | FTO (0.56) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL5149281 | 0.85 | FTO (0.55) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL9427469 | 0.85 | HPGD (0.56) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL1254421 | 0.85 | FTO (0.64) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL905219 | 0.84 | FTO (0.47) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL4885766 | 0.84 | FTO (0.47) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL15778575 | 0.84 | FTO (0.47) | FTOMAPTHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472227-B1 | A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0279308-B1 | Fluorescence polarization immunoassay for tetrahydrocannabinoids | ABBOTT LAB (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5463027-A | Fluorescence polarazation immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1995-10-31 | — | — | US | disclosed |
| US-5372949-A | Medical diagnosis | ABBOTT LABORATORIES (US) | 1994-12-13 | — | — | US | disclosed |
| US-5336622-A | Competitive binding using a fluorescent dye tracer; monitoring dosage in biological fluid; sensitivity; accuracy; efficiency | ABBOTT LABORATORIES (US) | 1994-08-09 | — | — | US | disclosed |
| US-5264373-A | Fluorescence polarization immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1993-11-23 | — | — | US | disclosed |
| US-5260441-A | Fluorescence polarization process for detecting unauthorized consumption of morphine | ABBOTT LABORATORIES (US) | 1993-11-09 | — | — | US | disclosed |
| US-5258512-A | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0242847-B1 | TRACERS FOR USE IN FLECAINIDE FLUORESCENCE POLARIZATION IMMUNOASSAY | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |
| EP-0457213-A2 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0402846-A2 | Fluorescence polarization immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4939264-A | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0373508-A2 | Barbiturate assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0279308-A2 | Fluorescence polarization immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |
| EP-0254120-A2 | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1988-01-27 | — | — | EP | disclosed |
| EP-0242847-A2 | Tracers for use in flecainide fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1987-10-28 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0199042-A1 | Procainamide assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | disclosed |