Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MAT2A | P31153 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783990 | 0.88 | TLR8 (0.44) | ESR2TLR8ALOX12ADORA3GSR | |
| SCHEMBL21422279 | 0.86 | ALDH1A1 (0.39) | ESR2TLR8MAPTMAPK1ALDH1A1 | |
| SCHEMBL19783855 | 0.84 | ADORA2A (0.40) | ESR2TLR8ALOX12ADORA3MAPT | |
| SCHEMBL19784126 | 0.84 | TLR8 (0.39) | ESR2TLR8ALOX12ADORA3GSR | |
| SCHEMBL19783860 | 0.82 | TLR8 (0.38) | ESR2TLR8MAT2AMAPK1ALDH1A1 | |
| SCHEMBL19783289 | 0.81 | TLR8 (0.37) | ESR2TLR8MAT2AMAPK1ALDH1A1 | |
| SCHEMBL21422263 | 0.81 | TLR8 (0.37) | ESR2TLR8MAT2A | |
| SCHEMBL19784123 | 0.81 | TLR8 (0.37) | ESR2TLR8MAT2AALDH1A1 | |
| SCHEMBL19783859 | 0.81 | TLR8 (0.37) | ESR2TLR8ALDH1A1 | |
| SCHEMBL19784119 | 0.81 | USP2 (0.39) | TLR8MAPTMAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-03 | — | — | US | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | DDT, BCHE, ACHE | ESR2 3670/4885TLR8 3552/4885GSK3A 2950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.