SCHEMBL19783863

SCHEMBL19783863

Cn1c(=O)n(Cc2ccc(Cl)nc2)c(=O)n1-c1ccc2nn(-c3cccnc3)cc2c1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 9/20 0.37
GRIN2B Q13224 9/20 0.37
KMT2A Q03164 1/20 0.36
TLR8 Q9NR97 1/20 0.35
MAT2A P31153 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
HIF1A Q16665 1/20 0.34
PIK3CD O00329 1/20 0.33
DCTPP1 Q9H773 1/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
P2RX3 P56373 1/20 0.33
USP1 O94782 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19784121 0.91 HIF1A (0.39) GRIN1GRIN2BTLR8MAT2AHIF1A
SCHEMBL21422279 0.89 ALDH1A1 (0.39) GRIN1GRIN2BKMT2ATLR8GAA
SCHEMBL19784122 0.87 GRIN1 (0.39) GRIN1GRIN2BKMT2ATLR8MAT2A
SCHEMBL19784119 0.86 USP2 (0.39) KMT2ATLR8MAPTLMNA
SCHEMBL19783855 0.84 ADORA2A (0.40) KMT2ATLR8MAT2AMAPT
SCHEMBL19784123 0.81 TLR8 (0.37) GRIN1GRIN2BTLR8MAT2A
SCHEMBL21422263 0.81 TLR8 (0.37) GRIN1GRIN2BTLR8MAT2A
SCHEMBL19783859 0.81 TLR8 (0.37) TLR8
SCHEMBL19783289 0.81 TLR8 (0.37) KMT2ATLR8MAT2AGAALMNA
SCHEMBL19783857 0.80 TLR8 (0.36) TLR8MAT2ALMNAL3MBTL1USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484877-B1 BICYCLIC COMPOUNDS AS PEST CONTROLLERS BAYER CROPSCIENCE AG (DE) 2020-07-01 EP disclosed
US-20190297887-A1 BICYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-10-03 US disclosed
WO-2018011111-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190297887-A1 BICYCLIC COMPOUNDS AS PESTICIDES DDT, BCHE, ACHE GRIN1 404/4885GRIN2B 649/4885KMT2A 3191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.