Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378108 | 0.85 | USP7 (0.47) | NPY5RGRM5DYRK1AUSP7HDAC6 | |
| SCHEMBL31144860 | 0.81 | DRD1 (0.47) | KCNH2DYRK1A | |
| SCHEMBL8103598 | 0.80 | DYRK1A (0.61) | KCNH2SCN10ANPY5RGRM5XDH | |
| SCHEMBL16112103 | 0.80 | NOTUM (0.46) | KCNH2SCN10ANPY5RSCN9A | |
| SCHEMBL7527075 | 0.79 | CLK4 (0.64) | XDHDYRK1AADORA2AADORA1 | |
| SCHEMBL1400240 | 0.79 | SCN9A (0.57) | SCN10AGRM5SCN9A | |
| SCHEMBL31145014 | 0.78 | IDO1 (0.54) | NPY5R | |
| SCHEMBL7864145 | 0.78 | IDO1 (0.54) | NPY5R | |
| SCHEMBL11955192 | 0.77 | NOTUM (0.52) | KCNH2SCN10ANPY5RHDAC6HDAC1 | |
| SCHEMBL31234168 | 0.77 | XDH (0.57) | XDHUSP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175804-A1 | NUCLEAR TRANSPORT MODULATORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-08-29 | — | — | WO | disclosed |
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |