SCHEMBL16112103

SCHEMBL16112103

FC(F)(F)Oc1ccc(-c2nc[nH]n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.46
NISCH Q9Y2I1 1/20 0.45
IDO1 P14902 1/20 0.43
SCN10A Q9Y5Y9 6/20 0.43
SCN5A Q14524 5/20 0.43
KCNH2 Q12809 3/20 0.43
SCN1A P35498 1/20 0.43
SCN9A Q15858 1/20 0.43
SCN2A Q99250 1/20 0.43
SCN8A Q9UQD0 1/20 0.43
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
NPY5R Q15761 1/20 0.40
CHRNA7 P36544 2/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
ADORA3 P0DMS8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16112675 0.86 NOTUM (0.35) NOTUMNISCHIDO1SCN10ASCN5A
SCHEMBL5381899 0.81 TRPA1 (0.49) NOTUMNISCHSCN5ASCN9A
SCHEMBL1978433 0.80 KCNH2 (0.48) SCN10AKCNH2SCN9ANPY5R
SCHEMBL2443970 0.78 KIF11 (0.45) NOTUMNISCHSCN2ANPC1RAB9A
SCHEMBL11955192 0.76 NOTUM (0.52) NOTUMSCN10AKCNH2SCN9ANPY5R
SCHEMBL445800 0.76 CLK4 (0.57) NOTUMNPC1RAB9AADORA3
SCHEMBL2095562 0.76 ALDH1A1 (0.35) ADORA3
SCHEMBL3664986 0.76 CLK4 (0.57) NOTUMNISCHSCN10ASCN5AKCNH2
SCHEMBL1653225 0.75 SMN1; SMN2 (0.39) NOTUMNPC1RAB9A
SCHEMBL13113062 0.74 XDH (0.60) NOTUMNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-17 US disclosed
CN-106572658-B Molecule and relative intermediate, composition and method with certain disinsection efficiencies 美国陶氏益农公司 2019-11-08 CN disclosed
CN-109476629-A The bicyclic derivatives that urea and thiocarbamide replace are as pesticides 先正达参股股份有限公司 2019-03-15 CN disclosed
CN-107573295-A Molecule and intermediate, composition and its correlation technique with certain agricultural chemicals effectiveness 美国陶氏益农公司 2018-01-12 CN disclosed
CN-105209450-B Molecules and intermediates having pesticidal utility, compositions and methods relating thereto 美国陶氏益农公司 2017-10-20 CN disclosed
CN-107105657-A Molecule and relative intermediate, composition and method with desinsection effectiveness 美国陶氏益农公司 2017-08-29 CN disclosed
CN-106572658-A Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto 美国陶氏益农公司 2017-04-19 CN disclosed
CN-103096977-B Fused heterocyclic compounds as ion channel modulators 吉利德科学公司 2017-02-15 CN disclosed
CN-103826452-B Pesticidal compositions and processes related thereto 陶氏益农公司 2017-02-01 CN disclosed
CN-105209450-A Molecules and intermediates having pesticidal utility, compositions and methods relating thereto DOW AGROSCIENCES LLC 2015-12-30 CN disclosed
CN-104602524-A Pesticidal compositions and methods related thereto DOW AGROSCIENCES LLC 2015-05-06 CN disclosed
WO-2014186027-A1 PROCESS FOR THE PREPARATION OF TRIARYL RHAMNOSE CARBAMATES DOW AGROSCIENCES LLC (US) 2014-11-20 WO disclosed
WO-2014158646-A1 IMPROVED PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES DOW AGROSCIENCES LLC (US) 2014-10-02 WO disclosed
WO-2014158644-A1 PROCESS FOR THE PREPARATION OF TRIARYL RHAMNOSE CARBAMATES DOW AGROSCIENCES LLC (US) 2014-10-02 WO disclosed
WO-2014158650-A1 PREPARATION OF TRIARYL RHAMNOSE CARBAMATES DOW AGROSCIENCES LLC (US) 2014-10-02 WO disclosed
WO-2014158647-A1 PREPARATION OF TRIARYL RHAMNOSE CARBAMATES DOW AGROSCIENCES LLC (US) 2014-10-02 WO disclosed
CN-103826452-A Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC 2014-05-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL APP, APBA1, PRNP NOTUM 810/4885NISCH 3844/4885IDO1 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.