Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16897251 | 0.88 | ALDH1A1 (0.39) | HDAC1HDAC2HDAC6L3MBTL1ALDH1A1 | |
| SCHEMBL19784442 | 0.85 | HDAC6 (0.42) | HDAC1HDAC2HDAC6L3MBTL1TSHR | |
| SCHEMBL31504950 | 0.82 | CA14 (0.47) | HDAC1HDAC2HDAC6GPR84PPARG | |
| SCHEMBL16713413 | 0.79 | CA14 (0.53) | HDAC1HDAC2HDAC6L3MBTL1GPR84 | |
| SCHEMBL2579658 | 0.79 | CA14 (0.53) | HDAC1HDAC2HDAC6L3MBTL1GPR84 | |
| SCHEMBL19784440 | 0.78 | HDAC1 (0.36) | HDAC1HDAC2HDAC6L3MBTL1KMT2A | |
| SCHEMBL2021066 | 0.77 | CA14 (0.44) | HDAC1HDAC2HDAC6GPR84PPARG | |
| SCHEMBL16897317 | 0.77 | CA14 (0.41) | HDAC1HDAC2HDAC6L3MBTL1TSHR | |
| SCHEMBL31216313 | 0.77 | GPR84 (0.53) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL2194683 | 0.76 | HDAC1 (0.46) | HDAC1HDAC2HDAC6GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369848-A1 | Conjugation Method for Carrier-Linked Prodrugs | Ascendls Pharma A/S (DK) | 2021-12-02 | — | — | US | disclosed |
| WO-2018011266-A1 | CONJUGATION METHOD FOR CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA A/S (DK) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369848-A1 | Conjugation Method for Carrier-Linked Prodrugs | UGT2B7, SLC10A1, UGT1A6 | HDAC1 716/4885HDAC2 753/4885HDAC6 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.