SCHEMBL19784913

SCHEMBL19784913

Brc1ccc(-c2ccc(/C(=C\c3ccc(-c4ccccc4)cc3)Cc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP19A1 P11511 4/20 0.45
TP53 P04637 2/20 0.44
ABCC4 O15439 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
PTGS1 P23219 1/20 0.42
HTT P42858 1/20 0.42
PDPK1 O15530 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
MME P08473 1/20 0.39
POLB P06746 1/20 0.39
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19832031 0.80 PTPN1 (0.38) ALDH1A1MAPK1CYP19A1MEN1KMT2A
SCHEMBL13283146 0.78 TP53 (0.38) TP53ABCC4LMNAGAATSHR
SCHEMBL25567374 0.78 PTGS1 (0.38) CYP19A1TP53ABCC4LMNAGAA
SCHEMBL23666532 0.77 AKR1C4 (0.42) ALDH1A1TP53ABCC4LMNAGAA
SCHEMBL25113117 0.77 AKR1C4 (0.42) ALDH1A1TP53ABCC4LMNAGAA
SCHEMBL19784912 0.77 ALDH1A1 (0.38) ALDH1A1MAPK1TP53ABCC4LMNA
SCHEMBL19660691 0.77 ALDH1A1 (0.56) ALDH1A1MAPK1CYP19A1TP53MEN1
SCHEMBL19660703 0.75 PTGS1 (0.39) ALDH1A1CYP19A1PTGS1MEN1KMT2A
SCHEMBL3851045 0.75 CYP3A4 (0.53) CYP19A1
SCHEMBL6675573 0.74 ESR1 (0.53) ALDH1A1MAPK1CYP19A1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed