SCHEMBL19784912

SCHEMBL19784912

Brc1ccc(-c2ccc(/C(=C\c3ccc(-c4ccccc4)c4ccccc34)Cc3ccccc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPK1 P28482 2/20 0.38
EGFR P00533 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
SRD5A2 P31213 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRM2 Q14416 1/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
LMNA P02545 2/20 0.33
NPC1 O15118 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19832033 0.80 ALDH1A1 (0.43) ALDH1A1MAPK1EGFRSMN1; SMN2MEN1
SCHEMBL19831883 0.80 PTGES (0.38) MAPK1EGFRSMN1; SMN2MEN1KMT2A
SCHEMBL19784913 0.77 ALDH1A1 (0.46) ALDH1A1MAPK1EGFRL3MBTL1SRD5A2
SCHEMBL19832031 0.72 PTPN1 (0.38) ALDH1A1MAPK1L3MBTL1SMN1; SMN2MEN1
SCHEMBL21707192 0.71 ACP3 (0.38) PDPK1GAA
SCHEMBL30979959 0.71 ALDH1A1 (0.67) ALDH1A1MAPK1SMN1; SMN2GRM2NPC1
SCHEMBL13950667 0.71 ALDH1A1 (0.67) ALDH1A1MAPK1SMN1; SMN2GRM2NPC1
SCHEMBL2499606 0.68 RAB9A (0.38) L3MBTL1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL2499605 0.68 RAB9A (0.38) L3MBTL1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL13098713 0.67 ALDH1A1 (0.57) ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed