SCHEMBL19784927

SCHEMBL19784927

Cc1ccc2ccc3c(N(c4ccccc4)c4ccc(C(C)(C)C)cc4)ccc4ccc1c2c43

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
CYP2D6 P10635 1/20 0.31
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12856442 0.93 MEN1 (0.36) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL14339342 0.93 MEN1 (0.36) TSHRALDH1A1CYP3A4TDP1L3MBTL1
SCHEMBL13948921 0.92 MEN1 (0.35) ALDH1A1CYP3A4TDP1L3MBTL1MEN1
SCHEMBL13367585 0.89 ALDH1A1 (0.53) TSHRALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL12856477 0.87 TSHR (0.34) TSHRRAB9ATP53SMN1; SMN2NR1H4
SCHEMBL13304296 0.86 TP53 (0.39) TP53SMN1; SMN2KEAP1NFE2L2NR1H4
SCHEMBL13948908 0.85 TSHR (0.33) TSHRNR1H4
SCHEMBL19660696 0.85 MEN1 (0.32) MEN1RAB9AKMT2ANPSR1TP53
SCHEMBL24425458 0.84 ALDH1A1 (0.37) TSHRALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL13321048 0.84 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012780-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2018-01-18 WO disclosed