SCHEMBL12856477

SCHEMBL12856477

CC(C)(C)c1ccc(N(c2ccc(C(C)(C)C)cc2)c2ccc3ccc4c(N(c5ccc(C(C)(C)C)cc5)c5ccc(C(C)(C)C)cc5)ccc5ccc2c3c54)cc1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.33
TYR P14679 1/20 0.33
SLC22A2 O15244 1/20 0.32
SLC22A1 O15245 1/20 0.32
SLC22A3 O75751 1/20 0.32
NR1H4 Q96RI1 1/20 0.31
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13948908 0.98 TSHR (0.33) TSHRLMNATYRSLC22A2SLC22A1
SCHEMBL13321310 0.95 KIF11 (0.38) TSHRLMNATYRTP53SMN1; SMN2
SCHEMBL14339342 0.94 MEN1 (0.36) TSHRLMNANR1H4TP53SMN1; SMN2
SCHEMBL12856442 0.94 MEN1 (0.36) TSHRLMNANR1H4TP53SMN1; SMN2
SCHEMBL13321048 0.94 TSHR (0.47) TSHRLMNANPC1RAB9A
SCHEMBL13948921 0.92 MEN1 (0.35) LMNANR1H4TP53SMN1; SMN2RAB9A
SCHEMBL23406395 0.91 NPC1 (0.32) SLC22A2SLC22A1SLC22A3NPC1RAB9A
SCHEMBL31488859 0.91
SCHEMBL13304296 0.89 TP53 (0.39) NR1H4TP53SMN1; SMN2
SCHEMBL12292385 0.89 ALDH1A1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240099094-A1 DISPLAY PANEL AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-03-21 US disclosed
EP-4333589-A1 DISPLAY PANEL AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2024-03-06 EP disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-11858949-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-11858949-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-02 US disclosed
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 US disclosed
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) 2023-12-14 US disclosed
US-8436344-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2013-05-07 US disclosed
EP-1437395-B1 Organic electroluminescent device LG DISPLAY CO LTD (KR) 2011-12-14 EP disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
US-20070292714-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-12-20 US disclosed
US-20070292714-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-12-20 US disclosed
EP-1790631-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE AOC1, EBPL, CYBA TSHR 4769/4885LMNA 250/4885TYR 25/4885
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE L1CAM, AOC2, AOC1 TSHR 3327/4885LMNA 2837/4885TYR 21/4885
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 TSHR 3770/4885LMNA 1450/4885TYR 1738/4885
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, C1S TSHR 2757/4885LMNA 1815/4885TYR 93/4885
US-11858949-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, MEN1, LEF1 TSHR 2462/4885LMNA 2055/4885TYR 1356/4885
US-20070292714-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same TYR, DDC, PNMT TSHR 3530/4885LMNA 954/4885TYR 1/4885
US-20230403926-A1 ORGANIC LIGHT-EMITTING DEVICE WITH IMPROVED LIFESPAN CHARACTERISTICS ELP1, ELOVL1, L3MBTL1 TSHR 4556/4885LMNA 1154/4885TYR 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.