SCHEMBL19785328

SCHEMBL19785328

O=C[C@H](O)[C@@H](O)[C@H](OC1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O[C@@H]1OC[C@@H](O)[C@@H](O)[C@@H]1O)[C@H](O)CO

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FGF1 P05230 1/20 0.35
IGF2R P11717 2/20 0.33
PTPN1 P18031 1/20 0.33
LGALS8 O00214 2/20 0.32
LGALS3 P17931 2/20 0.32
LGALS4 P56470 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAG P20916 2/20 0.32
GJA1 P17302 1/20 0.31
GJB2 P29033 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16909331 0.93 PTPN1 (0.36) FGF1PTPN1LGALS8LGALS3LGALS4
SCHEMBL17867165 0.89 IGF2R (0.41) IGF2RPTPN1LGALS8LGALS3LGALS4
SCHEMBL21206254 0.89 IGF2R (0.41) IGF2RPTPN1LGALS8LGALS3LGALS4
SCHEMBL16431846 0.89 IGF2R (0.41) IGF2RPTPN1LGALS8LGALS3LGALS4
SCHEMBL7627973 0.87 CD209 (0.37) FGF1IGF2RPTPN1LGALS8LGALS3
SCHEMBL15373700 0.84 LGALS8 (0.44) IGF2RLGALS8LGALS3LGALS4MEN1
SCHEMBL12362685 0.84 LGALS8 (0.44) IGF2RLGALS8LGALS3LGALS4MEN1
SCHEMBL14936334 0.84 LGALS8 (0.44) IGF2RLGALS8LGALS3LGALS4MEN1
SCHEMBL14936496 0.84 LGALS8 (0.44) IGF2RLGALS8LGALS3LGALS4MEN1
SCHEMBL17223127 0.84 LGALS8 (0.44) IGF2RLGALS8LGALS3LGALS4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10751362-B2 Compositions and methods for managing digestive disorders and a healthy microbiome METAGENICS, INC. (US) 2020-08-25 US disclosed
US-20180015032-A1 COMPOSITIONS AND METHODS FOR MANAGING DIGESTIVE DISORDERS AND A HEALTHY MICROBIOME WHITEHORSE CAPITAL ORIGINATION, LLC, AS AGENT 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180015032-A1 COMPOSITIONS AND METHODS FOR MANAGING DIGESTIVE DISORDERS AND A HEALTHY MICROBIOME FUCA2, SI, FUCA1 FGF1 303/4885IGF2R 79/4885PTPN1 3834/4885
US-10751362-B2 Compositions and methods for managing digestive disorders and a healthy microbiome FUCA2, SI, FUCA1 FGF1 303/4885IGF2R 79/4885PTPN1 3834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.