Sugi Predict

Sugi Predict / Compounds / SCHEMBL16909331

SCHEMBL16909331

SCHEMBL16909331

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nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 1/20 0.36
▸ MAG P20916 2/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ GJA1 P17302 1/20 0.34
▸ GJB2 P29033 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ LGALS8 O00214 1/20 0.33
▸ LGALS3 P17931 1/20 0.33
▸ LGALS4 P56470 1/20 0.33
▸ FGF1 P05230 1/20 0.33
▸ SELE P16581 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19785328 0.93 FGF1 (0.35) PTPN1MAGMEN1KMT2AGJA1
SCHEMBL16431846 0.87 IGF2R (0.41) PTPN1MEN1KMT2AGJA1GJB2
SCHEMBL17867165 0.87 IGF2R (0.41) PTPN1MEN1KMT2AGJA1GJB2
SCHEMBL21206254 0.87 IGF2R (0.41) PTPN1MEN1KMT2AGJA1GJB2
SCHEMBL29441467 0.86 SELE (0.43) MEN1KMT2ASELE
SCHEMBL31460959 0.86 MEN1 (0.39) PTPN1MEN1KMT2AGJA1GJB2
SCHEMBL17866964 0.86 MEN1 (0.39) PTPN1MEN1KMT2AGJA1GJB2
SCHEMBL17867221 0.86 MEN1 (0.39) PTPN1MEN1KMT2AGJA1GJB2
SCHEMBL7627973 0.84 CD209 (0.37) PTPN1MAGLMNALGALS8LGALS3
SCHEMBL12362685 0.84 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3147277-B1 LIPID MEMBRANE STRUCTURE FOR SIRNA INTRACELLULAR DELIVERY UNIV HOKKAIDO NAT UNIV CORP (JP) 2023-10-04 — — EP disclosed
US-10182987-B2 Lipid membrane structure for intracellular delivery of siRNA NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2019-01-22 — — US disclosed
US-20170273905-A1 LIPID MEMBRANE STRUCTURE FOR siRNA INTRACELLULAR DELIVERY NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2017-09-28 — — US disclosed
EP-3147277-A1 LIPID MEMBRANE STRUCTURE FOR siRNA INTRACELLULAR DELIVERY National University Corporation Hokkaido University (JP) 2017-03-29 — — EP disclosed
US-20150202154-A1 LIPID MEMBRANE STRUCTURE HAVING INTRANUCLEAR MIGRATING PROPERTY NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2015-07-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10182987-B2 Lipid membrane structure for intracellular delivery of siRNA NPC1L1, NPC1, ABCB4 PTPN1 4301/4885MAG 621/4885MEN1 1104/4885
US-20170273905-A1 LIPID MEMBRANE STRUCTURE FOR siRNA INTRACELLULAR DELIVERY NPC1L1, NPC1, SGMS1 PTPN1 4298/4885MAG 585/4885MEN1 1135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.