Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 15/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785402 | 0.88 | GABRG2 (0.48) | NR1H2NR1H3GABRA1GABRG2GABRB3 | |
| SCHEMBL31324195 | 0.81 | PSEN1 (0.41) | NR1H2GABRG2GABRB3GABRA5 | |
| SCHEMBL13696680 | 0.79 | CHRM2 (0.59) | NR1H2NR1H3GABRA1GABRG2GABRB3 | |
| SCHEMBL30022454 | 0.79 | CHRM2 (0.59) | NR1H2NR1H3GABRA1GABRG2GABRB3 | |
| SCHEMBL31370675 | 0.79 | L3MBTL1 (0.42) | NR1H2NR1H3USP30GABRA1GABRG2 | |
| SCHEMBL22648211 | 0.78 | GABRG2 (0.43) | NR1H2NR1H3GABRA1GABRG2GABRB3 | |
| SCHEMBL12961033 | 0.78 | CHRM2 (0.50) | NR1H2NR1H3GABRA1GABRG2GABRB3 | |
| SCHEMBL17973787 | 0.78 | TSPO (0.43) | NR1H2NR1H3GABRA1GABRG2GABRB3 | |
| SCHEMBL15456145 | 0.77 | CDK1 (0.49) | NR1H2NR1H3GABRG2GABRB3GABRA5 | |
| SCHEMBL12960820 | 0.77 | CHRM2 (0.49) | NR1H2NR1H3GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018013067-A1 | PROCESS FOR PREPARING CARBAZOLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DCLK2, DCLK1, PDCD2L | NR1H2 4029/4885NR1H3 3677/4885USP30 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.