Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026613 | 0.83 | NR1H2 (0.42) | ALDH1A1CNR2GABRG2GABRB3GABRA5 | |
| SCHEMBL16421934 | 0.83 | DYRK1A (0.61) | DYRK1A | |
| SCHEMBL16421935 | 0.81 | MAOA (0.46) | DYRK1ACNR2 | |
| SCHEMBL22648211 | 0.81 | GABRG2 (0.43) | GABRG2GABRB3GABRA5NR1H2L3MBTL1 | |
| SCHEMBL6300235 | 0.81 | NR1H2 (0.41) | ALDH1A1CNR2GABRG2GABRB3GABRA5 | |
| SCHEMBL8401504 | 0.80 | CNR2 (0.42) | DYRK1ACNR2NR1H2 | |
| SCHEMBL979540 | 0.80 | KDM4E (0.44) | ALDH1A1DYRK1ACNR2NR1H2ABCB1 | |
| SCHEMBL12685163 | 0.80 | NR1H2 (0.49) | ALDH1A1STSNR1H2 | |
| SCHEMBL20858533 | 0.79 | GABRG2 (0.48) | ALDH1A1GABRG2GABRB3GABRA5NR1H2 | |
| SCHEMBL24077249 | 0.79 | NR1H2 (0.46) | ALDH1A1STSNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018013067-A1 | PROCESS FOR PREPARING CARBAZOLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DCLK2, DCLK1, PDCD2L | ALDH1A1 1221/4885DYRK1A 62/4885CNR2 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.