Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785404 | 0.80 | ALDH1A1 (0.45) | CNR2DYRK1ANR1H2 | |
| SCHEMBL16727065 | 0.71 | L3MBTL1 (0.50) | CNR2PDE10AMTNR1ADYRK1AHTR6 | |
| SCHEMBL16727069 | 0.71 | L3MBTL1 (0.46) | CNR2PDE10AMTNR1ADYRK1AHTR6 | |
| SCHEMBL8132380 | 0.70 | ALDH1A1 (0.42) | CNR2PDE10AMTNR1AKDM4EMTNR1B | |
| SCHEMBL16421935 | 0.69 | MAOA (0.46) | CNR2DYRK1A | |
| SCHEMBL6300235 | 0.69 | NR1H2 (0.41) | CNR2EPHX2KDM4EAKR1C3NR1H2 | |
| SCHEMBL31026613 | 0.69 | NR1H2 (0.42) | CNR2KDM4EAKR1C3NR1H2 | |
| SCHEMBL979540 | 0.68 | KDM4E (0.44) | CNR2DYRK1AKDM4ENR1H2 | |
| SCHEMBL16421934 | 0.68 | DYRK1A (0.61) | DYRK1A | |
| SCHEMBL15778086 | 0.68 | L3MBTL1 (0.44) | CNR2PDE10AMTNR1ADYRK1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994544-A | PRODUCING A 5H-CHROMENO(3,4-F)QUINOLINE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-11-30 | — | — | US | disclosed |