Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716369 | 1.00 | SLC7A5 (0.33) | SLC7A5SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL203296 | 0.83 | GABRP (0.37) | SLC7A5SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL1248340 | 0.83 | GABRP (0.37) | SLC7A5SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL2717315 | 0.83 | GPR88 (0.35) | GPR88DPP4 | |
| SCHEMBL15910752 | 0.82 | GPR88 (0.35) | GPR88 | |
| SCHEMBL1025811 | 0.81 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1GRIK1 | |
| Hydrochloric Acid SCHEMBL4854700 | 0.79 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1GRIK1 | |
| SCHEMBL15910556 | 0.77 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL15910554 | 0.77 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1MAPT | |
| SCHEMBL13731404 | 0.77 | MEN1 (0.33) | MEN1HTTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336122-A1 | 1-pyrimidinyl- or 1-pyridinyl-2-amino benzimidazole derivatives and related compounds as inhibitors of protein kinases for the treatment of cancer | Vertex Pharmaceuticals Incorporated (US) | 2011-06-22 | — | — | EP | disclosed |